2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

Related Products

PDF 3.95 MB

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W704749
    7-Hydroxychlorpromazine hydrochloride
    7-Hydroxychlorpromazine hydrochloride is the active metabolite of Chlorpromazine (HY-12708). 7-Hydroxychlorpromazine hydrochloride can increase prolactin levels in rats. 7-Hydroxychlorpromazine hydrochloride can increase dopamine turnover and has a sedative effect. In addition, 7-Hydroxychlorpromazine hydrochloride can effectively inhibit amphetamine-induced stereotyped behavior in rats and is used in the study of psychosis.
    7-Hydroxychlorpromazine hydrochloride
  • HY-P10916
    Micafungin metabolite M1
    Micafungin metabolite M1 is an active metabolite of Micafungin (HY-17579), which is metabolized by arylsulfatase and exhibits antifungal activity. Micafungin metabolite M1 can be used for research on deep fungal infections caused by Candida and Aspergillus species.
    Micafungin metabolite M1
  • HY-133092
    Perphenazine sulfoxide
    Perphenazine sulfoxide is a sulphoxide metabolite of Perphenazine, formed by the oxidation of Perphenazine.
    Perphenazine sulfoxide
  • HY-B1984R
    p,p'-DDD (Standard)
    p,p'-DDD (Standard) is the analytical standard of p,p'-DDD (HY-B1984) . This product is intended for research and analytical applications. p,p'-DDD (4,4’-DDD) is an organochlorine insecticide, a major metabolite of p,p'-DDT. p,p'-DDD is an agonist at estrogen receptor α(ERα) and ERβ. p,p'-DDD increases DNA damage, apoptosis and necrosis in peripheral blood. p,p'-DDD stimulates cell proliferation in SKBR3 cells. p,p'-DDD activates the AP-1 transcription factor. p,p'-DDD decreases sleep times of barbiturates and steroids in rats.
    p,p'-DDD (Standard)
  • HY-116084R
    Trimethylamine N-oxide (Standard)
    Trimethylamine N-oxide (Standard) is the analytical standard of Trimethylamine N-oxide. This product is intended for research and analytical applications. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating the ROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating the TGF-β/smad2 signaling pathway.
    Trimethylamine N-oxide (Standard)
  • HY-W705140A
    Monohydroxy melphalan hydrochloride
    Monohydroxy melphalan hydrochloride (Hydroxymelphalan hydrochloride) is a degradation product of Melphalan (HY-17575), obtained through the hydrolysis of Melphalan in aqueous solutions (including cell culture media and human plasma).
    Monohydroxy melphalan hydrochloride
  • HY-131261R
    Ibuprofen alcohol (Standard)
    Ibuprofen alcohol (Standard) is the analytical standard of Ibuprofen alcohol. This product is intended for research and analytical applications. Ibuprofen alcohol, a nonsteroidal antiinflammatory agent (NSAID), exhibits very little activity for acid-sensing ion channels (ASICs).
    Ibuprofen alcohol (Standard)
  • HY-171362
    PSI-7410
    PSI-7410 is the metabolite of PSI-7851 (HY-14308). PSI-7851 is an inhibitor for HCV nonstructural protein 5B (NS5B) and exhibits antiviral activity.
    PSI-7410
  • HY-167637
    4-Hydroxyclonidine
    4-Hydroxyclonidine is a Clonidine (HY-12721) metabolite. 4-Hydroxyclonidine is as potent as Clonidine in displacing labeled Clonidine from the antibody.
    4-Hydroxyclonidine
  • HY-N5134A
    ara-GMP
    ara-GMP (ara-G monophosphate) is a metabolite of Arabinosylguanine (ara-G) (HY-N0097A). ara-GMP incorporates into replicating DNA , initiates S phase-specific apoptosis. ara-GMP can be used for the research of cancer, such as T-cell acute lymphoblastic leukemia.
    ara-GMP
  • HY-W198670
    1,2-Diacetylbenzene
    1,2-Diacetylbenzene, a γ-diketone metabolite derived from the neurotoxic solvent 1,2-diethylbenzene, is an aromatic hydrocarbon known for its reactivity with proteins.
    1,2-Diacetylbenzene
  • HY-138818
    N,O-Didesmethylvenlafaxine
    N,O-Didesmethylvenlafaxine (NODVFX) is a metabolite of Venlafaxine (VFX; HY-B0196). Venlafaxine (Wy 45030) is an orally active, potent serotonin (5-HT)/norepinephrine (NE) reuptake dual inhibitor.
    N,O-Didesmethylvenlafaxine
  • HY-118093R
    N-benzoyl-L-aspartic acid (Standard)
    N-benzoyl-L-aspartic acid (Standard) is the analytical standard of N-benzoyl-L-aspartic acid. This product is intended for research and analytical applications. N-benzoyl-L-aspartic acid, a major metabolite of benzyl glucosinolate, can be used for modification of peptides or proteins.
    N-benzoyl-L-aspartic acid (Standard)
  • HY-176891
    Cyslopentenyl cytosine triphosphoric
    Cyslopentenyl cytosine triphosphoric is an active metabolite of the antitumor nucleoside analogue cyclopentenyl cytosine (CPEC) within cells. Cyslopentenyl cytosine triphosphoric can inhibit CTP synthetase and deplete the pools of cytidine nucleotides. Cyslopentenyl cytosine triphosphoric can be used for the research of cancer, such as leukemia.
    Cyslopentenyl cytosine triphosphoric
  • HY-W1006349
    1,2,3,4,6,7,8-Heptachlorodibenzofuran
    1,2,3,4,6,7,8-Heptachlorodibenzofuran (1,2,3,4,6,7,8-HpCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 1,2,3,4,6,7,8-Heptachlorodibenzofuran has been found in the soil near municipal waste incinerators, in freshwater fish, and in human breastmilk.
    1,2,3,4,6,7,8-Heptachlorodibenzofuran
  • HY-W009713R
    3,4,5-Trimethoxyphenylacetic acid (Standard)
    Cyclogalegenin (Standard) is the analytical standard of Cyclogalegenin. This product is intended for research and analytical applications. Cyclogalegenin (Cyclogalegigenin) is a isoprenoid that can be isolated from Astragalus galegiformis. Cyclogalegenin is the enantiomer of Cycloastragenol.
    3,4,5-Trimethoxyphenylacetic acid (Standard)
  • HY-W716866
    10α-Hydroxy-exo-THC
    10α-hydroxy-exo-THC is a cannabinoid compound, a metabolite of Δ9-THC, and can be found in cannabis. 10α-hydroxy-exo-THC can serve as an analytical reference standard for cannabinoid compounds .
    10α-Hydroxy-exo-THC
  • HY-172561
    15-Keto treprostinil sodium
    15-Keto treprostinil sodium is an impurity in Treprostinil (HY-100441). Treprostinil is a potent DP1 and EP2 agonist.
    15-Keto treprostinil sodium
  • HY-167643
    Hydroxy tipelukast
    Hydroxy tipelukast (Compound MN-002), the metabolite of Compound MN-001, is an orally active phenoxyalkylcarboxylic acid. Hydroxy tipelukast inhibits liver steatosis, lobular inflammation, hepatic ballooning, and hepatic scarring, and reduces liver hydroxyproline levels. Hydroxy tipelukast is promising for research of non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH).
    Hydroxy tipelukast
  • HY-W293109
    AB-PINACA 3-Carboxyindazole metabolite
    		Control
    AB-PINACA 3-Carboxyindazole metabolite is a metabolite of APINAC.
    AB-PINACA 3-Carboxyindazole metabolite
Cat. No. Product Name / Synonyms Application Reactivity